Hofmann Rearrangement and Curtius Reaction Mechanism - Primary Amides & Acid Chlorides to Amines
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YouTubeThe Organic Chemistry Tutor
Hofmann Rearrangement and Curtius Reaction Mechanism - Primary Amides & Acid Chlorides to Amines
This organic chemistry video tutorial provides the mechanism of the hofmann and curtius rearrangement reaction in which a primary amide and an acid chloride is converted to a primary amine. The reactions each passes through an isocyanate intermediate, a carbamic acid and undergoes decarboxylation to produce the amine. The Hofmann rearrangement ...
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