To differentiate into T cells, immature thymocytes must engage, through their antigen-specific T-cell receptor, peptides derived from self proteins presented by cortical epithelial cells in the thymus ...

Calcium signaling is essential during thymocyte development. It seems that calcium oscillations trigger thymocytes to become immotile, prolonging interactions with stromal cells that are critical for ...

Researchers from Osaka University find that the tyrosine kinase Csk inhibits germinal center B cell signaling, thereby decreasing the production of reactive oxygen species and apoptosis, and promoting ...

In a newly published review, Professor Xiao-Jun Huang's team at Peking University People's Hospital explore how haploidentical hematopoietic stem cell transplantation (haplo-HSCT), once limited by ...