Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

By recreating a fetal liver niche, FLOs show how liver and immune cells co-develop. Learn more about new groundbreaking ...

Fatty liver disease isn’t just a concern for the overweight—it can strike people of healthy weight and diet, and now scientists think they know why. Two genes previously linked to cancer, RNF43 and ...

Dr. Saurabh Sethi notes that most people believe sugar affects weight. However, it can strongly influence your liver.

As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths. While the treatment options for this aggressive type of cancer remain ...

Organoids refer to small-scale organs made up of diverse cell types, exhibiting structures and functions akin to actual organs. Unlike conventional cell cultures, organoids better replicate human ...

The development of hepatocellular carcinoma, liver cancer, is known to involve abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, ...

Breakthrough Therapy Designation is intended to expedite the development and review of medicines that are intended to treat a serious or life-threatening condition and have shown preliminary clinical ...

Researchers at MIT and Harvard have found that following a high-fat diet such as keto can cause dramatic changes to liver ...

Drugs that fail in late stages of development create one of the biggest challenges in global healthcare. In fact, less than 10% of the drugs that move into clinical development survive to approval.