Inflammation has long been a warning sign in kidney clinics, a red flag that often appears years before a patient tips into ...

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli. The ...

Researchers uncover a previously unrecognized mechanism that may accelerate polycystic kidney disease. For people with polycystic kidney disease (PKD), life can be a constant cycle of symptoms: aches ...

Researchers at the University of Tsukuba have developed a novel mouse model that allows them to induce dysfunction in only one kidney. Using this model, they uncovered the molecular mechanisms behind ...

Niigata, Japan - The gold standard test for predicting the onset of diabetic kidney disease is albuminuria. However, detecting albuminuria alone has limited sensitivity and specificity in end-stage ...

A new study from Aarhus University demonstrates that a protein known for treating cardiovascular diseases also affects a mechanism in the kidney that reabsorbs proteins. This finding could lead to new ...

University of Texas at Dallas scientists have discovered a previously unknown "housekeeping" process in kidney cells that ejects unwanted content, resulting in cells that rejuvenate themselves and ...

A review article published in the journal Frontiers in Physiology by researchers affiliated with the Federal University of São Paulo (UNIFESP) in Brazil discusses the mechanisms whereby SARS-CoV-2 ...

ALTHOUGH many extensive investigations in animals 1–3 have demonstrated the existence of renal medullary hyperosmolality suggestive of a counter-current mechanism of urine concentration, direct ...