A newly identified and rare genetic variant slows the growth of mutated blood stem cells and reduces the risk of leukemia.

A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report, and it reduces the risk of leukemia.

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...

The blood system changes over time: a subset of stem cells outcompete their neighbors and gradually take over blood production. In addition, the blood stem cell reservoir shrinks and becomes dominated ...

Tumor-infiltrating clonal hematopoiesis increased the risk of disease recurrence or death among patients with cancer. TET2 mutations were the strongest genetic predictor of tumor-infiltrating clonal ...

Unlike a solid organ transplantation, which requires moving an intact organ from donor to recipient, a hematopoietic cell transplant (HCT) involves the transferal of just some of the donor’s blood ...

New insights reveal how hidden genetic mutations could be silently fueling heart disease in middle-aged adults, paving the way for personalized prevention strategies. In a recent study published in ...

Results from METIS (EF-25), an international, multicenter phase III randomized study evaluating the efficacy and safety of tumor treating fields (TTFields) therapy in NSCLC patients with brain ...

The study is among the first to look at the potential impacts of clonal dynamics on patients with lower-risk myelodysplastic syndromes (MDS). However, most of what scientists know about the impact of ...

PLYMOUTH MEETING, Pa., Nov. 13, 2024 /PRNewswire/ -- INOVIO (NASDAQ:INO), a biotechnology company focused on developing and commercializing DNA medicines to help treat and protect people from ...