In January 2024, the FDA updated its guidance on CAR-T therapies, emphasizing the need for enhanced safety and quality measures. This update followed a series of warnings regarding the risk of T cell ...

T cells play a big role in bringing cell and gene therapies to patients. Despite this clinical potential, scientists developing T cell therapies such as chimeric antigen receptor (CAR)-T cells, ...

Artificial intelligence-supported cell imaging could help laboratories to set defensible quality thresholds for living ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

In the pursuit of faster and more reliable recombinant protein production, transient transfection has emerged as a cornerstone of early biopharmaceutical development. Compared to stable transfection, ...

Integrated analytical workflows are transforming cell line development by combining faster screening and streamlined decision-making.

Ribosomes—the tiny factories that build proteins in our cells—don't all work with the same efficiency. Researchers from Japan ...

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide ...

Successfully producing large quantities of biotherapeutics, including monoclonal antibodies and recombinant protein products, depends on robust and reliable cell line development (CLD). Issues that ...